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Conolidine’s analgesic outcomes stem from its interaction with non-opioid pain pathways. As opposed to opioids, which bind to µ-opioid receptors while in the central nervous method, conolidine modulates alternate molecular targets. A Science Advances study uncovered that conolidine interacts with the atypical chemokine receptor ACKR3/CXCR7, whic

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